Identification of a Novel De Novo Mutation Associated with PRKAG2 Cardiac Syndrome and Early Onset of Heart Failure

Yang Liu; Rong Bai; Lin Wang; Cuntai Zhang; Ruifu Zhao; Deli Wan; Xinshan Chen; Gabriel Caceres; Daniel Barr; Hector Barajas-Martinez; Charles Antzelevitch; Dan Hu

doi:10.1371/journal.pone.0064603

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Open Access

Peer-reviewed

Research Article

Identification of a Novel De Novo Mutation Associated with PRKAG2 Cardiac Syndrome and Early Onset of Heart Failure

Yang Liu,

Affiliations Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, Cardiovascular Department, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangzhou, China
⨯
Rong Bai,

Affiliation Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Lin Wang,

Affiliation Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Cuntai Zhang,

Affiliation Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Ruifu Zhao,

Affiliation Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Deli Wan,

Affiliation Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Xinshan Chen,

Affiliation Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Gabriel Caceres,

Affiliation Department of Molecular Genetics and Experimental Cardiology, Masonic Medical Research Laboratory, Utica, New York, United States of America
⨯
Daniel Barr,

Affiliation Department of Chemistry and Biochemistry, Utica College, Utica, New York, United States of America
⨯
Hector Barajas-Martinez,

Affiliation Department of Molecular Genetics and Experimental Cardiology, Masonic Medical Research Laboratory, Utica, New York, United States of America
⨯
Charles Antzelevitch,

Affiliation Department of Molecular Genetics and Experimental Cardiology, Masonic Medical Research Laboratory, Utica, New York, United States of America
⨯
Dan Hu

* E-mail: dianah@mmrl.edu

Affiliation Department of Molecular Genetics and Experimental Cardiology, Masonic Medical Research Laboratory, Utica, New York, United States of America
⨯

Identification of a Novel De Novo Mutation Associated with PRKAG2 Cardiac Syndrome and Early Onset of Heart Failure

Yang Liu,
Rong Bai,
Lin Wang,
Cuntai Zhang,
Ruifu Zhao,
Deli Wan,
Xinshan Chen,
Gabriel Caceres,
Daniel Barr,
Hector Barajas-Martinez

Published: May 31, 2013
https://doi.org/10.1371/journal.pone.0064603

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