Pharmacokinetics Study of Recombinant Hirudin in the Plasma of Rats Using Chromogenic Substrate, ELISA, and Radioisotope Assays

Open Access

Peer-reviewed

Research Article

Su-yun Jiang ,

* E-mail: syjiangsy@263.net

Affiliations Dalian University of Technology, Dalian, China, Dalian Institute for Food and Drug Control, Dalian, China
⨯
Jian Jiao,

Affiliation Dalian Institute for Food and Drug Control, Dalian, China
⨯
Ting-ting Zhang,

Affiliation Dalian Institute for Food and Drug Control, Dalian, China
⨯
Yong-ping Xu

Affiliation Dalian University of Technology, Dalian, China
⨯

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Pharmacokinetics
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Recombination-based assay
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Thrombin
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Enzyme-linked immunoassays
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Trichloroacetic acid precipitation
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Radioactivity
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Elimination half-life calculation
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Enzyme assays
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