Detection of JC Virus-Specific Immune Responses in a Novel Humanized Mouse Model

Chen Sabrina Tan; Thomas A. Broge Jr; Edward Seung; Vlad Vrbanac; Raphael Viscidi; Jennifer Gordon; Andrew M. Tager; Igor J. Koralnik

doi:10.1371/journal.pone.0064313

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Open Access

Peer-reviewed

Research Article

Detection of JC Virus-Specific Immune Responses in a Novel Humanized Mouse Model

Chen Sabrina Tan ,

* E-mail: ctan@bidmc.harvard.edu

Affiliations Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Center for Virology and Vaccine Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Division of NeuroVirology, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
⨯
Thomas A. Broge Jr,

Affiliations Center for Virology and Vaccine Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Division of NeuroVirology, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
⨯
Edward Seung,

Affiliation Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
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Vlad Vrbanac,

Affiliation Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
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Raphael Viscidi,

Affiliation Johns Hopkins Medical Center, Baltimore, Maryland, United States of America
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Jennifer Gordon,

Affiliations Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Andrew M. Tager,

Affiliation Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
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Igor J. Koralnik

Affiliations Center for Virology and Vaccine Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Division of NeuroVirology, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
⨯

Detection of JC Virus-Specific Immune Responses in a Novel Humanized Mouse Model

Chen Sabrina Tan,
Thomas A. Broge Jr,
Edward Seung,
Vlad Vrbanac,
Raphael Viscidi,
Jennifer Gordon,
Andrew M. Tager,
Igor J. Koralnik

Published: May 20, 2013
https://doi.org/10.1371/journal.pone.0064313

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