Hydrogen Sulfide Prevents Hydrogen Peroxide-Induced Activation of Epithelial Sodium Channel through a PTEN/PI(3,4,5)P3 Dependent Pathway

Jianing Zhang; Shuo Chen; Huibin Liu; Bingkun Zhang; Ying Zhao; Ke Ma; Dan Zhao; Qiushi Wang; Heping Ma; Zhiren Zhang

doi:10.1371/journal.pone.0064304

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Peer-reviewed

Research Article

Hydrogen Sulfide Prevents Hydrogen Peroxide-Induced Activation of Epithelial Sodium Channel through a PTEN/PI(3,4,5)P₃ Dependent Pathway

Jianing Zhang,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Shuo Chen,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Huibin Liu,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Bingkun Zhang,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Ying Zhao,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Ke Ma,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Dan Zhao,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Qiushi Wang,

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯
Heping Ma ,

* E-mail: zhirenz@yahoo.com (ZZ); heping.ma@emory.edu (HM)

Affiliation Department of Physiology, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Zhiren Zhang

* E-mail: zhirenz@yahoo.com (ZZ); heping.ma@emory.edu (HM)

Affiliation Departments of Clinical Pharmacy and Cardiology, the 2nd Affiliated Hospital, Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, P.R. China
⨯

Hydrogen Sulfide Prevents Hydrogen Peroxide-Induced Activation of Epithelial Sodium Channel through a PTEN/PI(3,4,5)P₃ Dependent Pathway

Jianing Zhang,
Shuo Chen,
Huibin Liu,
Bingkun Zhang,
Ying Zhao,
Ke Ma,
Dan Zhao,
Qiushi Wang,
Heping Ma,
Zhiren Zhang

Published: May 31, 2013
https://doi.org/10.1371/journal.pone.0064304

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