Rat Model for Dominant Dystrophic Epidermolysis Bullosa: Glycine Substitution Reduces Collagen VII Stability and Shows Gene-Dosage Effect

• Alexander Nyström,

  Affiliation Department of Dermatology, University Freiburg Medical Center, Freiburg, Germany

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• Jens Buttgereit,

  Affiliations Max Delbück Center for Molecular Medicine (MDC), Campus Berlin-Buch, Berlin, Germany, Experimental and Clinical Research Center (ECRC), Berlin, Germany

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• Michael Bader,

  Affiliation Max Delbück Center for Molecular Medicine (MDC), Campus Berlin-Buch, Berlin, Germany

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• Tatiana Shmidt,

  Affiliations Max Delbück Center for Molecular Medicine (MDC), Campus Berlin-Buch, Berlin, Germany, Experimental and Clinical Research Center (ECRC), Berlin, Germany

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• Cemil Özcelik,

  Current address: Helios Albert-Schweitzer-Klinik, Northeim, Germany

  Affiliations Max Delbück Center for Molecular Medicine (MDC), Campus Berlin-Buch, Berlin, Germany, Experimental and Clinical Research Center (ECRC), Berlin, Germany

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• Ingrid Hausser,

  Affiliation Department of Dermatology, University of Heidelberg, Heidelberg, Germany

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• Leena Bruckner-Tuderman ,

  * E-mail: bruckner-tuderman@uniklinik-freiburg.de

  Affiliations Department of Dermatology, University Freiburg Medical Center, Freiburg, Germany, Freiburg Institute for Advanced Studies, School of Life Sciences, LifeNet, University of Freiburg, Freiburg, Germany

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• Johannes S. Kern

  Affiliation Department of Dermatology, University Freiburg Medical Center, Freiburg, Germany

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