A UDP-X Diphosphatase from Streptococcus pneumoniae Hydrolyzes Precursors of Peptidoglycan Biosynthesis

Krisna C. Duong-Ly; Hyun Nyun Woo; Christopher A. Dunn; WenLian Xu; Andrej Babič; Maurice J. Bessman; L. Mario Amzel; Sandra B. Gabelli

doi:10.1371/journal.pone.0064241

Loading metrics

Open Access

Peer-reviewed

Research Article

A UDP-X Diphosphatase from Streptococcus pneumoniae Hydrolyzes Precursors of Peptidoglycan Biosynthesis

Krisna C. Duong-Ly,

Current address: Fox Chase Cancer Center, Cancer Biology Program, Philadelphia, Pennsylvania, United States of America

Affiliation Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Hyun Nyun Woo,

Current address: Case Western Reserve University School of Dental Medicine, Cleveland, Ohio, United States of America

Affiliation Department of Biology and McCollum-Pratt Institute, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Christopher A. Dunn,

Current address: Laboratory of Molecular Gerontology, NIA, National Institutes of Health, Baltimore, Maryland, United States of America

Affiliation Department of Biology and McCollum-Pratt Institute, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
WenLian Xu,

Current address: JOINN Laboratories, Germantown, Maryland, United States of America

Affiliation Department of Biology and McCollum-Pratt Institute, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Andrej Babič,

Affiliation School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland
⨯
Maurice J. Bessman,

Affiliation Department of Biology and McCollum-Pratt Institute, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
L. Mario Amzel ,

* E-mail: mamzel@jhmi.edu (LMA); gabelli@jhmi.edu (SBG)

Affiliation Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Sandra B. Gabelli

* E-mail: mamzel@jhmi.edu (LMA); gabelli@jhmi.edu (SBG)

Affiliations Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯

A UDP-X Diphosphatase from Streptococcus pneumoniae Hydrolyzes Precursors of Peptidoglycan Biosynthesis

Krisna C. Duong-Ly,
Hyun Nyun Woo,
Christopher A. Dunn,
WenLian Xu,
Andrej Babič,
Maurice J. Bessman,
L. Mario Amzel,
Sandra B. Gabelli

Published: May 15, 2013
https://doi.org/10.1371/journal.pone.0064241

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Monomers
Is the Subject Area "Monomers" applicable to this article?

Thanks for your feedback.
Hydrolases
Is the Subject Area "Hydrolases" applicable to this article?

Thanks for your feedback.
Hydrolysis
Is the Subject Area "Hydrolysis" applicable to this article?

Thanks for your feedback.
Pneumococcus
Is the Subject Area "Pneumococcus" applicable to this article?

Thanks for your feedback.
Dimers
Is the Subject Area "Dimers" applicable to this article?

Thanks for your feedback.
Peptidoglycans
Is the Subject Area "Peptidoglycans" applicable to this article?

Thanks for your feedback.
Ribozymes
Is the Subject Area "Ribozymes" applicable to this article?

Thanks for your feedback.
Enzyme structure
Is the Subject Area "Enzyme structure" applicable to this article?

Thanks for your feedback.