Utility of Host Markers Detected in Quantiferon Supernatants for the Diagnosis of Tuberculosis in Children in a High-Burden Setting

Novel N. Chegou; Anne K. Detjen; Lani Thiart; Elisabetta Walters; Anna M. Mandalakas; Anneke C. Hesseling; Gerhard Walzl

doi:10.1371/journal.pone.0064226

Loading metrics

Open Access

Peer-reviewed

Research Article

Utility of Host Markers Detected in Quantiferon Supernatants for the Diagnosis of Tuberculosis in Children in a High-Burden Setting

Novel N. Chegou ,

* E-mail: novel@sun.ac.za

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
⨯
Anne K. Detjen,

Affiliations Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa, The International Union Against Tuberculosis and Lung Disease, North America Office, International Union Against Tuberculosis and Lung Disease, New York, New York, United States of America
⨯
Lani Thiart,

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
⨯
Elisabetta Walters,

Affiliation Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
⨯
Anna M. Mandalakas,

Affiliation Section on Retrovirology and Global Health, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Anneke C. Hesseling,

Affiliation Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
⨯
Gerhard Walzl

Affiliation DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa
⨯

Utility of Host Markers Detected in Quantiferon Supernatants for the Diagnosis of Tuberculosis in Children in a High-Burden Setting

Novel N. Chegou,
Anne K. Detjen,
Lani Thiart,
Elisabetta Walters,
Anna M. Mandalakas,
Anneke C. Hesseling,
Gerhard Walzl

Published: May 15, 2013
https://doi.org/10.1371/journal.pone.0064226

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Tuberculosis
Is the Subject Area "Tuberculosis" applicable to this article?

Thanks for your feedback.
Tuberculosis diagnosis and management
Is the Subject Area "Tuberculosis diagnosis and management" applicable to this article?

Thanks for your feedback.
Mycobacterium tuberculosis
Is the Subject Area "Mycobacterium tuberculosis" applicable to this article?

Thanks for your feedback.
Diagnostic medicine
Is the Subject Area "Diagnostic medicine" applicable to this article?

Thanks for your feedback.
HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
HIV diagnosis and management
Is the Subject Area "HIV diagnosis and management" applicable to this article?

Thanks for your feedback.
HIV infections
Is the Subject Area "HIV infections" applicable to this article?

Thanks for your feedback.
Miliary tuberculosis
Is the Subject Area "Miliary tuberculosis" applicable to this article?

Thanks for your feedback.