Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development

Lisa Shaw; Sharon F. Sneddon; Leo Zeef; Susan J. Kimber; Daniel R. Brison

doi:10.1371/journal.pone.0064192

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Peer-reviewed

Research Article

Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development

Lisa Shaw ,

Contributed equally to this work with: Lisa Shaw, Sharon F. Sneddon

Current address: School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, United Kingdom

Affiliations Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom, Department of Reproductive Medicine, Old St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Sharon F. Sneddon ,

Contributed equally to this work with: Lisa Shaw, Sharon F. Sneddon

Current address: School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Affiliations Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom, Department of Reproductive Medicine, Old St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Leo Zeef,

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Susan J. Kimber,

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
⨯
Daniel R. Brison

* E-mail: Daniel.Brison@manchester.ac.uk

Affiliations Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom, Department of Reproductive Medicine, Old St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, United Kingdom
⨯

Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development

Lisa Shaw,
Sharon F. Sneddon,
Leo Zeef,
Susan J. Kimber,
Daniel R. Brison

Published: May 22, 2013
https://doi.org/10.1371/journal.pone.0064192

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Gene expression
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