High Doses of Ursodeoxycholic Acid Up-Regulate the Expression of Placental Breast Cancer Resistance Protein in Patients Affected by Intrahepatic Cholestasis of Pregnancy

Francesco Azzaroli; Maria Elena Raspanti; Patrizia Simoni; Marco Montagnani; Andrea Lisotti; Paolo Cecinato; Rosario Arena; Giuliana Simonazzi; Antonio Farina; Nicola Rizzo; Giuseppe Mazzella

doi:10.1371/journal.pone.0064101

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Open Access

Peer-reviewed

Research Article

High Doses of Ursodeoxycholic Acid Up-Regulate the Expression of Placental Breast Cancer Resistance Protein in Patients Affected by Intrahepatic Cholestasis of Pregnancy

Francesco Azzaroli ,

* E-mail: francesco.azzaroli@unibo.it

Affiliations Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy, Centre for Applied Biomedical Research, S.Orsola-Malpighi Hospital, Bologna, Italy
⨯
Maria Elena Raspanti,

Affiliations Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy, Centre for Applied Biomedical Research, S.Orsola-Malpighi Hospital, Bologna, Italy
⨯
Patrizia Simoni,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Marco Montagnani,

Affiliations Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy, Centre for Applied Biomedical Research, S.Orsola-Malpighi Hospital, Bologna, Italy
⨯
Andrea Lisotti,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Paolo Cecinato,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Rosario Arena,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Giuliana Simonazzi,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Antonio Farina,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Nicola Rizzo,

Affiliation Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy
⨯
Giuseppe Mazzella

Affiliations Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Italy, Centre for Applied Biomedical Research, S.Orsola-Malpighi Hospital, Bologna, Italy
⨯

High Doses of Ursodeoxycholic Acid Up-Regulate the Expression of Placental Breast Cancer Resistance Protein in Patients Affected by Intrahepatic Cholestasis of Pregnancy

Francesco Azzaroli,
Maria Elena Raspanti,
Patrizia Simoni,
Marco Montagnani,
Andrea Lisotti,
Paolo Cecinato,
Rosario Arena,
Giuliana Simonazzi,
Antonio Farina,
Nicola Rizzo

Published: May 24, 2013
https://doi.org/10.1371/journal.pone.0064101

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