ABT-263 Enhances Sensitivity to Metformin and 2-Deoxyglucose in Pediatric Glioma by Promoting Apoptotic Cell Death

Open Access

Peer-reviewed

Research Article

Jane Levesley ,

* E-mail: j.levesley@leeds.ac.uk (JL); s.lawler@leeds.ac.uk (SL)

Affiliation Translational Neuro-Oncology Group, Leeds Institute of Molecular Medicine, University of Leeds, St James’s University Hospital, Leeds, United Kingdom
⨯
Lynette Steele,

Affiliation Translational Neuro-Oncology Group, Leeds Institute of Molecular Medicine, University of Leeds, St James’s University Hospital, Leeds, United Kingdom
⨯
Claire Taylor,

Affiliation Genomics Facility, Leeds Institute of Molecular Medicine, University of Leeds, St James’s University Hospital, Leeds, United Kingdom
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Priyank Sinha,

Affiliation Translational Neuro-Oncology Group, Leeds Institute of Molecular Medicine, University of Leeds, St James’s University Hospital, Leeds, United Kingdom
⨯
Sean E. Lawler

* E-mail: j.levesley@leeds.ac.uk (JL); s.lawler@leeds.ac.uk (SL)

Affiliation Translational Neuro-Oncology Group, Leeds Institute of Molecular Medicine, University of Leeds, St James’s University Hospital, Leeds, United Kingdom
⨯

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Apoptosis
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Pediatrics
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Glioma cells
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Cell death
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Cancer treatment
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Glycolysis
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Cell metabolism
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Glioma
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