FTY720/Fingolimod, a Sphingosine Analogue, Reduces Amyloid-β Production in Neurons

• Nobumasa Takasugi,

  Current address: Department of Pharmacology, Juntendo University School of Medicine, Tokyo, Japan

  Affiliations Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, The University of Tokyo, Tokyo, Japan

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• Tomoki Sasaki,

  Affiliation Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

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• Ihori Ebinuma,

  Affiliation Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

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• Satoko Osawa,

  Affiliation Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

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• Hayato Isshiki,

  Affiliations Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, The University of Tokyo, Tokyo, Japan

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• Koji Takeo,

  Affiliation Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan

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• Taisuke Tomita ,

  * E-mail: taisuke@mol.f.u-tokyo.ac.jp

  Affiliations Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, The University of Tokyo, Tokyo, Japan

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• Takeshi Iwatsubo

  Affiliations Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan, Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, The University of Tokyo, Tokyo, Japan

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