Low Concentrations of Metformin Selectively Inhibit CD133+ Cell Proliferation in Pancreatic Cancer and Have Anticancer Action

Open Access

Peer-reviewed

Research Article

Low Concentrations of Metformin Selectively Inhibit CD133⁺ Cell Proliferation in Pancreatic Cancer and Have Anticancer Action

Shanmiao Gou ,

Contributed equally to this work with: Shanmiao Gou, Pengfei Cui

* E-mail: chunyouwang52@126.com (CW); gousm@163.com (SG)

Affiliation Pancreatic Disease Institute, Department of General Surgery, Union Hospital, HUST, Wuhan, P. R. China
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Pengfei Cui ,

Contributed equally to this work with: Shanmiao Gou, Pengfei Cui

Affiliation Pancreatic Disease Institute, Department of General Surgery, Union Hospital, HUST, Wuhan, P. R. China
⨯
Xiangsheng Li,

Affiliation Pancreatic Disease Institute, Department of General Surgery, Union Hospital, HUST, Wuhan, P. R. China
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Pengfei Shi,

Affiliation Pancreatic Disease Institute, Department of General Surgery, Union Hospital, HUST, Wuhan, P. R. China
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Tao Liu,

Affiliation Pancreatic Disease Institute, Department of General Surgery, Union Hospital, HUST, Wuhan, P. R. China
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Chunyou Wang

* E-mail: chunyouwang52@126.com (CW); gousm@163.com (SG)

Affiliation Pancreatic Disease Institute, Department of General Surgery, Union Hospital, HUST, Wuhan, P. R. China
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Pancreatic cancer
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Cancer treatment
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Flow cytometry
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Cancer stem cells
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Stem cell therapy
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Apoptosis
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Cell cycle and cell division
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Cell proliferation
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