Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

Joanna A. Korecka; Ronald E. van Kesteren; Eva Blaas; Sonia O. Spitzer; Jorke H. Kamstra; August B. Smit; Dick F. Swaab; Joost Verhaagen; Koen Bossers

doi:10.1371/journal.pone.0063862

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Open Access

Peer-reviewed

Research Article

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

Joanna A. Korecka ,

* E-mail: j.korecka@nin.knaw.nl

Affiliation Department of Neuroregeneration, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
⨯
Ronald E. van Kesteren,

Affiliation Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit, Amsterdam, The Netherlands
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Eva Blaas,

Affiliation Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit, Amsterdam, The Netherlands
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Sonia O. Spitzer,

Current address: MRC Center for Stem Cell & Regenerative Medicine and Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Affiliation Department of Neuroregeneration, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
⨯
Jorke H. Kamstra,

Affiliation Institute for Environmental Studies (IVM), Vrije Universiteit, Amsterdam, The Netherlands
⨯
August B. Smit,

Affiliation Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit, Amsterdam, The Netherlands
⨯
Dick F. Swaab,

Affiliation Department of Neuropsychiatric Disorders, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
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Joost Verhaagen,

Affiliations Department of Neuroregeneration, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, Vrije Universiteit, Amsterdam, The Netherlands
⨯
Koen Bossers

Affiliation Department of Neuroregeneration, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
⨯

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

Joanna A. Korecka,
Ronald E. van Kesteren,
Eva Blaas,
Sonia O. Spitzer,
Jorke H. Kamstra,
August B. Smit,
Dick F. Swaab,
Joost Verhaagen,
Koen Bossers

Published: May 28, 2013
https://doi.org/10.1371/journal.pone.0063862

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Neuronal differentiation
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Gene expression
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Mitochondria
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Gene regulation
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Neurons
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Cell differentiation
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