Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation

• Sonja Zeilinger,

  Affiliation Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Brigitte Kühnel,

  Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Norman Klopp,

  Affiliations Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Hannover Unified Biobank, Hannover Medical School, Hannover, Germany

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• Hansjörg Baurecht,

  Affiliations Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany, Graduate School of Information Science in Health (GSISH), Technische Universität München, Munich, Germany

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• Anja Kleinschmidt,

  Affiliation Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Christian Gieger,

  Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Stephan Weidinger,

  Affiliation Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany

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• Eva Lattka,

  Affiliation Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Jerzy Adamski,

  Affiliations Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, Neuherberg, Germany, Chair of Experimental Genetics, Technische Universität München, Munich, Germany

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• Annette Peters,

  Affiliations Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Konstantin Strauch,

  Affiliations Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

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• Melanie Waldenberger ,

  Contributed equally to this work with: Melanie Waldenberger, Thomas Illig

  * E-mail: waldenberger@helmholtz-muenchen.de

  Affiliation Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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• Thomas Illig

  Contributed equally to this work with: Melanie Waldenberger, Thomas Illig

  Affiliations Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Hannover Unified Biobank, Hannover Medical School, Hannover, Germany

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