A Kir6.2 Pore Mutation Causes Inactivation of ATP-Sensitive Potassium Channels by Disrupting PIP2-Dependent Gating

Open Access

Peer-reviewed

Research Article

A Kir6.2 Pore Mutation Causes Inactivation of ATP-Sensitive Potassium Channels by Disrupting PIP₂-Dependent Gating

Jeremy D. Bushman,

Current address: Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America

Affiliation Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon, United States of America
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Qing Zhou,

Affiliation Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon, United States of America
⨯
Show-Ling Shyng

* E-mail: shyngs@ohsu.edu

Affiliation Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon, United States of America
⨯

Ion channel gating
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Neomycins
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Glycine
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Potassium channels
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Membrane potential
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Proline
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Chemiluminescence
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Substitution mutation
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