Pemetrexed Induced Thymidylate Synthase Inhibition in Non-Small Cell Lung Cancer Patients: A Pilot Study with 3′-Deoxy-3′-[18F]fluorothymidine Positron Emission Tomography

Open Access

Peer-reviewed

Research Article

Pemetrexed Induced Thymidylate Synthase Inhibition in Non-Small Cell Lung Cancer Patients: A Pilot Study with 3′-Deoxy-3′-[¹⁸F]fluorothymidine Positron Emission Tomography

Virginie Frings ,

* E-mail: v.frings@vumc.nl

Affiliation Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
⨯
Astrid A. M. van der Veldt,

Affiliation Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
⨯
Ronald Boellaard,

Affiliation Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
⨯
Gerarda J. M. Herder,

Affiliation Department of Pulmonary Diseases, St. Antonius Hospital, Nieuwegein, The Netherlands
⨯
Elisa Giovannetti,

Affiliation Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Richard Honeywell,

Affiliation Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
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Godefridus J. Peters,

Affiliation Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
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Erik Thunnissen,

Affiliation Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Otto S. Hoekstra,

Affiliation Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
⨯
Egbert F. Smit

Affiliation Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands
⨯

Cancer treatment
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Non-small cell lung cancer
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Positron emission tomography
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Cancers and neoplasms
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Bone marrow
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Thymidines
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Blood plasma
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Compartment models
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