Comparison of Treatment Effect Estimates for Pharmacological Randomized Controlled Trials Enrolling Older Adults Only and Those including Adults: A Meta-Epidemiological Study

• Valérie Seegers,

  Affiliations Assistance Publique-Hôpitaux de Paris, Hôpital Hôtel-Dieu, Paris, France, INSERM U738, Paris, France

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• Ludovic Trinquart,

  Affiliations Assistance Publique-Hôpitaux de Paris, Hôpital Hôtel-Dieu, Paris, France, INSERM U738, Paris, France, Université Paris Descartes – Sorbonne Paris Cité, Paris, France, French Cochrane Centre, Paris, France

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• Isabelle Boutron,

  Affiliations Assistance Publique-Hôpitaux de Paris, Hôpital Hôtel-Dieu, Paris, France, INSERM U738, Paris, France, Université Paris Descartes – Sorbonne Paris Cité, Paris, France, French Cochrane Centre, Paris, France

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• Philippe Ravaud

  * E-mail: philippe.ravaud@htd.aphp.fr

  Affiliations Assistance Publique-Hôpitaux de Paris, Hôpital Hôtel-Dieu, Paris, France, INSERM U738, Paris, France, Université Paris Descartes – Sorbonne Paris Cité, Paris, France, French Cochrane Centre, Paris, France, Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, United States of America

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