Effects of Biliverdin Administration on Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation in Rats

Junko Kosaka; Hiroshi Morimatsu; Toru Takahashi; Hiroko Shimizu; Susumu Kawanishi; Emiko Omori; Yasumasa Endo; Naofumi Tamaki; Manabu Morita; Kiyoshi Morita

doi:10.1371/journal.pone.0063606

Loading metrics

Open Access

Peer-reviewed

Research Article

Effects of Biliverdin Administration on Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation in Rats

Junko Kosaka,

Affiliation Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Hiroshi Morimatsu ,

* E-mail: morima-h@md.okayama-u.ac.jp

Affiliation Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Toru Takahashi,

Affiliations Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, Faculty of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan
⨯
Hiroko Shimizu,

Affiliation Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Susumu Kawanishi,

Affiliation Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Emiko Omori,

Affiliation Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Yasumasa Endo,

Affiliation Department of Preventive Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Naofumi Tamaki,

Affiliation Department of Preventive Dentistry, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
⨯
Manabu Morita,

Affiliation Department of Preventive Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯
Kiyoshi Morita

Affiliation Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⨯

Effects of Biliverdin Administration on Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation in Rats

Junko Kosaka,
Hiroshi Morimatsu,
Toru Takahashi,
Hiroko Shimizu,
Susumu Kawanishi,
Emiko Omori,
Yasumasa Endo,
Naofumi Tamaki,
Manabu Morita,
Kiyoshi Morita

Published: May 7, 2013
https://doi.org/10.1371/journal.pone.0063606

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Resuscitation
Is the Subject Area "Resuscitation" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Severe blood loss
Is the Subject Area "Severe blood loss" applicable to this article?

Thanks for your feedback.
Bilirubin
Is the Subject Area "Bilirubin" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Antioxidants
Is the Subject Area "Antioxidants" applicable to this article?

Thanks for your feedback.
Edema
Is the Subject Area "Edema" applicable to this article?

Thanks for your feedback.