The Catalytic Roles of P185 and T188 and Substrate-Binding Loop Flexibility in 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni

• Chi-Ching Hwang ,

  * E-mail: cchwang@kmu.edu.tw

  Affiliation Department of Biochemistry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

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• Yi-Hsun Chang,

  Affiliation Department of Biochemistry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

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• Hwei-Jen Lee,

  Affiliation Department and Graduate Institute of Biochemistry, National Defense Medical Center, Taipei, Taiwan

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• Tzu-Pin Wang,

  Affiliation Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan

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• Yu-Mei Su,

  Affiliation Department of Biochemistry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

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• Hsin-Wei Chen,

  Affiliation Department of Biochemistry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

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• Po-Huang Liang

  Affiliation Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

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