Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection

Zhehao Zhang; Jen-Chyong Wang; William Howells; Peng Lin; Arpana Agrawal; Howard J. Edenberg; Jay A. Tischfield; Marc A. Schuckit; Laura J. Bierut; Alison Goate; John P. Rice

doi:10.1371/journal.pone.0063526

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Open Access

Peer-reviewed

Research Article

Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection

Zhehao Zhang ,

* E-mail: zhang.zhehao@wustl.edu (ZZ); john@zork.wustl.edu (JPR)

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
Jen-Chyong Wang,

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
William Howells,

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
Peng Lin,

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
Arpana Agrawal,

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
Howard J. Edenberg,

Affiliation Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Jay A. Tischfield,

Affiliation LSB 136, Rutgers University, Piscataway, New Jersey, United States of America
⨯
Marc A. Schuckit,

Affiliation Department of Psychiatry, University of California San Diego, La Jolla, California, United States of America
⨯
Laura J. Bierut,

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
Alison Goate,

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯
John P. Rice

* E-mail: zhang.zhehao@wustl.edu (ZZ); john@zork.wustl.edu (JPR)

Affiliation Washington University School of Medicine, Department of Psychiatry, St. Louis, Missouri, United States of America
⨯

Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection

Zhehao Zhang,
Jen-Chyong Wang,
William Howells,
Peng Lin,
Arpana Agrawal,
Howard J. Edenberg,
Jay A. Tischfield,
Marc A. Schuckit,
Laura J. Bierut,
Alison Goate

Published: May 14, 2013
https://doi.org/10.1371/journal.pone.0063526

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