Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin

Wesley S. Bond; Patricia Y. Akinfenwa; Laszlo Perlaky; Mary Y. Hurwitz; Richard L. Hurwitz; Patricia Chévez-Barrios

doi:10.1371/journal.pone.0063519

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Research Article

Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin

Wesley S. Bond,

Affiliations Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Center for Cell and Gene Therapy, Houston, Texas, United States of America, Texas Children's Cancer and Hematology Centers, Houston, Texas, United States of America
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Patricia Y. Akinfenwa,

Affiliations Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Center for Cell and Gene Therapy, Houston, Texas, United States of America, Texas Children's Cancer and Hematology Centers, Houston, Texas, United States of America
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Laszlo Perlaky,

Affiliations Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Texas Children's Cancer and Hematology Centers, Houston, Texas, United States of America
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Mary Y. Hurwitz,

Affiliations Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Center for Cell and Gene Therapy, Houston, Texas, United States of America, Texas Children's Cancer and Hematology Centers, Houston, Texas, United States of America
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Richard L. Hurwitz ,

Contributed equally to this work with: Richard L. Hurwitz, Patricia Chévez-Barrios

Affiliations Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America, Center for Cell and Gene Therapy, Houston, Texas, United States of America, Texas Children's Cancer and Hematology Centers, Houston, Texas, United States of America, The Retinoblastoma Center of Houston, Houston, Texas, United States of America
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Patricia Chévez-Barrios

Contributed equally to this work with: Richard L. Hurwitz, Patricia Chévez-Barrios

* E-mail: pchevez-barrios@tmhs.org

Affiliations Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas, United States of America, The Retinoblastoma Center of Houston, Houston, Texas, United States of America
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Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin

Wesley S. Bond,
Patricia Y. Akinfenwa,
Laszlo Perlaky,
Mary Y. Hurwitz,
Richard L. Hurwitz,
Patricia Chévez-Barrios

Published: June 24, 2013
https://doi.org/10.1371/journal.pone.0063519

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