Overexpression of EGFR in Head and Neck Squamous Cell Carcinoma Is Associated with Inactivation of SH3GL2 and CDC25A Genes

Guru Prasad Maiti; Pinaki Mondal; Nupur Mukherjee; Amlan Ghosh; Susmita Ghosh; Sanjib Dey; Jayanta Chakrabarty; Anup Roy; Jaydip Biswas; Susanta Roychoudhury; Chinmay Kumar Panda

doi:10.1371/journal.pone.0063440

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Open Access

Peer-reviewed

Research Article

Overexpression of EGFR in Head and Neck Squamous Cell Carcinoma Is Associated with Inactivation of SH3GL2 and CDC25A Genes

Guru Prasad Maiti,

Affiliation Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India
⨯
Pinaki Mondal,

Affiliation Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India
⨯
Nupur Mukherjee,

Affiliation Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India
⨯
Amlan Ghosh,

Affiliations Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India, Department of Zoology, Presidency University, Kolkata, India
⨯
Susmita Ghosh,

Affiliations Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
⨯
Sanjib Dey,

Affiliation Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India
⨯
Jayanta Chakrabarty,

Affiliation Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India
⨯
Anup Roy,

Affiliation North Bengal Medical College, Sushruta Nagar,Darjeeling, West Bengal, India
⨯
Jaydip Biswas,

Affiliation Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India
⨯
Susanta Roychoudhury,

Affiliation Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India
⨯
Chinmay Kumar Panda

* E-mail: ckpanda.cnci@gmail.com

Affiliation Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India
⨯

Overexpression of EGFR in Head and Neck Squamous Cell Carcinoma Is Associated with Inactivation of SH3GL2 and CDC25A Genes

Guru Prasad Maiti,
Pinaki Mondal,
Nupur Mukherjee,
Amlan Ghosh,
Susmita Ghosh,
Sanjib Dey,
Jayanta Chakrabarty,
Anup Roy,
Jaydip Biswas,
Susanta Roychoudhury

Published: May 10, 2013
https://doi.org/10.1371/journal.pone.0063440

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Head and neck cancers
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Protein expression
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Hyperexpression techniques
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Lung and intrathoracic tumors
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DNA methylation
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Head and neck squamous cell carcinoma
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Small interfering RNA
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Gene expression
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