Areca Nut Extract Induces Pyknotic Necrosis in Serum-Starved Oral Cells via Increasing Reactive Oxygen Species and Inhibiting GSK3β: An Implication for Cytopathic Effects in Betel Quid Chewers

• Wen-Tsai Ji,

  Affiliation Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, College of Science, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan

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• Cheng-I Lee,

  Affiliation Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, College of Science, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan

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• Jeff Yi-Fu Chen,

  Affiliation Department of Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan

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• Ya-Ping Cheng,

  Affiliation Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, College of Science, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan

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• Sheng-Ru Yang,

  Affiliation Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, College of Science, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan

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• Jung-Hua Chen,

  Affiliation Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, College of Science, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan

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• Hau-Ren Chen

  * E-mail: biohrc@ccu.edu.tw

  Affiliation Department of Life Science, Institute of Molecular Biology and Institute of Biomedical Science, College of Science, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan

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