Fine-Mapping and Genetic Analysis of the Loci Affecting Hepatic Iron Overload in Mice

Xin Guo; Zhuzhen Zhang; Fan Zhang; Yunlong Tao; Peng An; Qian Wu; Chia-Yu Wang; Mitchell D. Knutson; Fudi Wang

doi:10.1371/journal.pone.0063280

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Open Access

Peer-reviewed

Research Article

Fine-Mapping and Genetic Analysis of the Loci Affecting Hepatic Iron Overload in Mice

Xin Guo,

Affiliations Key Laboratory of Nutrition and Metabolism, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China, Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯
Zhuzhen Zhang,

Affiliations Key Laboratory of Nutrition and Metabolism, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China, Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯
Fan Zhang,

Affiliations Key Laboratory of Nutrition and Metabolism, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China, Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯
Yunlong Tao,

Affiliations Key Laboratory of Nutrition and Metabolism, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China, Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯
Peng An,

Affiliations Key Laboratory of Nutrition and Metabolism, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China, Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯
Qian Wu,

Affiliations Key Laboratory of Nutrition and Metabolism, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China, Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯
Chia-Yu Wang,

Affiliation Department of Food Science and Human Nutrition, University of Florida, Gainesville, Florida, United States of America
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Mitchell D. Knutson,

Affiliation Department of Food Science and Human Nutrition, University of Florida, Gainesville, Florida, United States of America
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Fudi Wang

* E-mail: fwang@zju.edu.cn

Affiliation Department of Nutrition, Institute of Nutrition and Food Safety, School of Public Health, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou, P.R. China
⨯

Fine-Mapping and Genetic Analysis of the Loci Affecting Hepatic Iron Overload in Mice

Xin Guo,
Zhuzhen Zhang,
Fan Zhang,
Yunlong Tao,
Peng An,
Qian Wu,
Chia-Yu Wang,
Mitchell D. Knutson,
Fudi Wang

Published: May 10, 2013
https://doi.org/10.1371/journal.pone.0063280

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