Metabolic Turnover of Synaptic Proteins: Kinetics, Interdependencies and Implications for Synaptic Maintenance

Open Access

Peer-reviewed

Research Article

Laurie D. Cohen,

Affiliations Technion Faculty of Medicine, Lorry Lokey Center for Life Sciences and Engineering, Technion, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Center for Life Sciences and Engineering, Technion, Haifa, Israel
⨯
Rina Zuchman,

Affiliation Smoler Proteomics Center, Faculty of Biology, Technion, Haifa, Israel
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Oksana Sorokina,

Affiliation Institute for Adaptive and Neural Computation, University of Edinburgh, Edinburgh, United Kingdom
⨯
Anke Müller,

Affiliations Leibniz-Institute for Neurobiology, Magdeburg, Germany, Institute for Pharmacology and Toxicology, Otto-von-Guericke University, Magdeburg, Germany
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Daniela C. Dieterich,

Affiliations Leibniz-Institute for Neurobiology, Magdeburg, Germany, Institute for Pharmacology and Toxicology, Otto-von-Guericke University, Magdeburg, Germany
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J. Douglas Armstrong,

Affiliation Institute for Adaptive and Neural Computation, University of Edinburgh, Edinburgh, United Kingdom
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Tamar Ziv,

Affiliation Smoler Proteomics Center, Faculty of Biology, Technion, Haifa, Israel
⨯
Noam E. Ziv

* E-mail: noamz@netvision.net.il

Affiliations Technion Faculty of Medicine, Lorry Lokey Center for Life Sciences and Engineering, Technion, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Center for Life Sciences and Engineering, Technion, Haifa, Israel
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Protein metabolism
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Neurons
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Protein synthesis
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Synapses
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Stable isotope labeling by amino acids in cell culture
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Neuronal dendrites
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Lysine
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Synaptic vesicles
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