Identification and Characterization of the Direct Interaction between Methotrexate (MTX) and High-Mobility Group Box 1 (HMGB1) Protein

• Yuki Kuroiwa ,

  Contributed equally to this work with: Yuki Kuroiwa, Yoichi Takakusagi

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Yoichi Takakusagi ,

  Contributed equally to this work with: Yuki Kuroiwa, Yoichi Takakusagi

  Affiliations Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Tomoe Kusayanagi,

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Kouji Kuramochi,

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Takahiko Imai,

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Tomoko Hirayama,

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Ichiaki Ito,

  Affiliation Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Michiteru Yoshida,

  Affiliation Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Kengo Sakaguchi,

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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• Fumio Sugawara

  * E-mail: sugawara@rs.noda.tus.ac.jp

  Affiliation Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, Yamazaki, Noda, Chiba, Japan

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