N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins

• Braden Sweeting,

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, The Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

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• Eric Brown,

  Current address: Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

  Affiliation Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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• M. Qasim Khan,

  Affiliations The Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• Avijit Chakrabartty,

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, The Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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• Emil F. Pai

  * E-mail: address: pai@hera.med.utoronto.ca

  Affiliations Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, The Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

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