Adaptive Mutations and Replacements of Virulence Traits in the Escherichia coli O104:H4 Outbreak Population

Lionel Guy; Cecilia Jernberg; Jenny Arvén Norling; Sofie Ivarsson; Ingela Hedenström; Öjar Melefors; Ulrika Liljedahl; Lars Engstrand; Siv G. E. Andersson

doi:10.1371/journal.pone.0063027

Loading metrics

Open Access

Peer-reviewed

Research Article

Adaptive Mutations and Replacements of Virulence Traits in the Escherichia coli O104:H4 Outbreak Population

Lionel Guy,

Affiliation Department of Molecular Evolution, Cell and Molecular Biology, Science for Life Laboratory, Biomedical Centre, Uppsala University, Uppsala, Sweden
⨯
Cecilia Jernberg,

Affiliation Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden
⨯
Jenny Arvén Norling,

Affiliation Department of Molecular Evolution, Cell and Molecular Biology, Science for Life Laboratory, Biomedical Centre, Uppsala University, Uppsala, Sweden
⨯
Sofie Ivarsson,

Affiliation Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden
⨯
Ingela Hedenström,

Affiliation Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden
⨯
Öjar Melefors,

Affiliations Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden, Department of Microbiology, Tumor- and Cell Biology, Karolinska Institutet, Stockholm, Sweden
⨯
Ulrika Liljedahl,

Affiliation Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala, Sweden
⨯
Lars Engstrand,

Affiliations Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden, Department of Microbiology, Tumor- and Cell Biology, Karolinska Institutet, Stockholm, Sweden
⨯
Siv G. E. Andersson

* E-mail: siv.andersson@icm.uu.se

Affiliation Department of Molecular Evolution, Cell and Molecular Biology, Science for Life Laboratory, Biomedical Centre, Uppsala University, Uppsala, Sweden
⨯

Adaptive Mutations and Replacements of Virulence Traits in the Escherichia coli O104:H4 Outbreak Population

Lionel Guy,
Cecilia Jernberg,
Jenny Arvén Norling,
Sofie Ivarsson,
Ingela Hedenström,
Öjar Melefors,
Ulrika Liljedahl,
Lars Engstrand,
Siv G. E. Andersson

Published: May 10, 2013
https://doi.org/10.1371/journal.pone.0063027

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Antibiotic resistance
Is the Subject Area "Antibiotic resistance" applicable to this article?

Thanks for your feedback.
Phylogenetics
Is the Subject Area "Phylogenetics" applicable to this article?

Thanks for your feedback.
Toxins
Is the Subject Area "Toxins" applicable to this article?

Thanks for your feedback.
Sequence alignment
Is the Subject Area "Sequence alignment" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Bacterial genomics
Is the Subject Area "Bacterial genomics" applicable to this article?

Thanks for your feedback.
Bacteriophages
Is the Subject Area "Bacteriophages" applicable to this article?

Thanks for your feedback.