Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson’s Disease

Yang Liu; Yubo Guo; Sai An; Yuyang Kuang; Xi He; Haojun Ma; Jianfeng Li; Jing Lv; Ning Zhang; Chen Jiang

doi:10.1371/journal.pone.0062905

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Open Access

Peer-reviewed

Research Article

Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson’s Disease

Yang Liu,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Yubo Guo,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Sai An,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Yuyang Kuang,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Xi He,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Haojun Ma,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Jianfeng Li,

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯
Jing Lv,

Affiliation Department of Life Sciences and Technology, Caliper-a PerkinElmer Company, Alameda, California, United States of America
⨯
Ning Zhang,

Affiliation Department of Life Sciences and Technology, Caliper-a PerkinElmer Company, Alameda, California, United States of America
⨯
Chen Jiang

* E-mail: jiangchen@shmu.edu.cn

Affiliation Key Laboratory of Smart Drug Delivery, Ministry of Education and PLA, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China
⨯

Targeting Caspase-3 as Dual Therapeutic Benefits by RNAi Facilitating Brain-Targeted Nanoparticles in a Rat Model of Parkinson’s Disease

Yang Liu,
Yubo Guo,
Sai An,
Yuyang Kuang,
Xi He,
Haojun Ma,
Jianfeng Li,
Jing Lv,
Ning Zhang,
Chen Jiang

Published: May 13, 2013
https://doi.org/10.1371/journal.pone.0062905

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03 Sep 2013
05:53 GMT
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author name spelling error Posted by jingluus on 03 Sep 2013 at 05:53 GMT

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