Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model

Alexander Kalb; Clarissa von Haefen; Marco Sifringer; Annalena Tegethoff; Nadine Paeschke; Mariya Kostova; Aarne Feldheiser; Claudia D. Spies

doi:10.1371/journal.pone.0062679

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Peer-reviewed

Research Article

Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model

Alexander Kalb ,

Contributed equally to this work with: Alexander Kalb, Clarissa von Haefen

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Clarissa von Haefen ,

Contributed equally to this work with: Alexander Kalb, Clarissa von Haefen

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Marco Sifringer,

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Annalena Tegethoff,

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Nadine Paeschke,

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Mariya Kostova,

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Aarne Feldheiser,

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯
Claudia D. Spies

* E-mail: claudia.spies@charite.de

Affiliation Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité, Universitätsmedizin Berlin, Germany
⨯

Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model

Alexander Kalb,
Clarissa von Haefen,
Marco Sifringer,
Annalena Tegethoff,
Nadine Paeschke,
Mariya Kostova,
Aarne Feldheiser,
Claudia D. Spies

Published: May 3, 2013
https://doi.org/10.1371/journal.pone.0062679

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