Neutralizing Antibodies in Patients with Chronic Hepatitis C, Genotype 1, against a Panel of Genotype 1 Culture Viruses: Lack of Correlation to Treatment Outcome

Jannie Pedersen; Tanja B. Jensen; Thomas H. R. Carlsen; Kristian Schønning; Peer Brehm Christensen; Alex Lund Laursen; Henrik Krarup; Jens Bukh; Nina Weis

doi:10.1371/journal.pone.0062674

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Open Access

Peer-reviewed

Research Article

Neutralizing Antibodies in Patients with Chronic Hepatitis C, Genotype 1, against a Panel of Genotype 1 Culture Viruses: Lack of Correlation to Treatment Outcome

Jannie Pedersen,

Affiliations Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark, Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Tanja B. Jensen,

Affiliations Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Thomas H. R. Carlsen,

Affiliations Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Kristian Schønning,

Affiliation Department of Clinical Microbiology, Copenhagen University Hospital, Hvidovre, Denmark
⨯
Peer Brehm Christensen,

Affiliation Department of Infectious Diseases, Odense University Hospital, Odense, Denmark
⨯
Alex Lund Laursen,

Affiliation Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
⨯
Henrik Krarup,

Affiliation Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
⨯
Jens Bukh ,

* E-mail: ninaweis@dadlnet.dk (NW); jbukh@sund.ku.dk (JB)

Affiliations Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Nina Weis

* E-mail: ninaweis@dadlnet.dk (NW); jbukh@sund.ku.dk (JB)

Affiliations Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
⨯

Neutralizing Antibodies in Patients with Chronic Hepatitis C, Genotype 1, against a Panel of Genotype 1 Culture Viruses: Lack of Correlation to Treatment Outcome

Jannie Pedersen,
Tanja B. Jensen,
Thomas H. R. Carlsen,
Kristian Schønning,
Peer Brehm Christensen,
Alex Lund Laursen,
Henrik Krarup,
Jens Bukh,
Nina Weis

Published: May 7, 2013
https://doi.org/10.1371/journal.pone.0062674

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Hepatitis C virus
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Antibodies
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Protease inhibitor therapy
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Chronic hepatitis
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Sequence alignment
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