Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells

• Vishwaroop Mulay ,

  Contributed equally to this work with: Vishwaroop Mulay, Peta Wood

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Peta Wood ,

  Contributed equally to this work with: Vishwaroop Mulay, Peta Wood

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Melanie Manetsch,

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Masoud Darabi,

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Rose Cairns,

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Monira Hoque,

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Karen Cecilia Chan,

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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• Meritxell Reverter,

  Affiliation Departament de Biologia Cel·lular, Immunologia i Neurociències, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

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• Anna Álvarez-Guaita,

  Affiliation Departament de Biologia Cel·lular, Immunologia i Neurociències, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

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• Kerry-Anne Rye,

  Affiliations Lipid Research Group, Heart Research Institute, Newtown, Sydney, New South Wales, Australia, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia

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• Carles Rentero,

  Affiliation Departament de Biologia Cel·lular, Immunologia i Neurociències, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

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• Joerg Heeren,

  Affiliation Department of Biochemistry and Molecular Biology II: Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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• Carlos Enrich,

  Affiliation Departament de Biologia Cel·lular, Immunologia i Neurociències, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

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• Thomas Grewal

  * E-mail: thomas.grewal@sydney.edu.au

  Affiliation Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

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