Environmental Oxygen Tension Regulates the Energy Metabolism and Self-Renewal of Human Embryonic Stem Cells

Open Access

Peer-reviewed

Research Article

Catherine E. Forristal,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
David R. Christensen,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Fay E. Chinnery,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Raffaella Petruzzelli,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Kate L. Parry,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Tilman Sanchez-Elsner,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Franchesca D. Houghton

* E-mail: F.D.Houghton@soton.ac.uk

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯

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Glucose metabolism
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Glucose
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Hypoxia
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Pluripotency
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Energy metabolism
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Pyruvate
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Cell metabolism
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Small interfering RNA
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