Identification of Residues of SARS-CoV nsp1 That Differentially Affect Inhibition of Gene Expression and Antiviral Signaling

Open Access

Peer-reviewed

Research Article

Andrew R. Jauregui,

Affiliation Infectious Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
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Dhruti Savalia,

Affiliation Infectious Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
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Virginia K. Lowry,

Affiliation Infectious Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
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Cara M. Farrell,

Affiliation Infectious Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
⨯
Marc G. Wathelet

* E-mail: mwathelet@lrri.org

Affiliations Infectious Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America, Department of Pathology, University of New Mexico, Albuquerque, New Mexico, United States of America
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Signal inhibition
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Virus effects on host gene expression
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SARS coronavirus
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Gene expression
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Antiviral immune response
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Transfection
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CAT assay
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Mutation
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