Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital

G. Michael Taylor; Katie Tucker; Rachel Butler; Alistair W. G. Pike; Jamie Lewis; Simon Roffey; Philip Marter; Oona Y-C Lee; Houdini H. T. Wu; David E. Minnikin; Gurdyal S. Besra; Pushpendra Singh; Stewart T. Cole; Graham R. Stewart

doi:10.1371/journal.pone.0062406

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Open Access

Peer-reviewed

Research Article

Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital

G. Michael Taylor ,

* E-mail: gm.taylor@Surrey.ac.uk

Affiliation Department of Microbial and Cellular Science, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, United Kingdom
⨯
Katie Tucker,

Affiliation Department of Archaeology, University of Winchester, Winchester, United Kingdom
⨯
Rachel Butler,

Affiliation Department of Microbial and Cellular Science, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, United Kingdom
⨯
Alistair W. G. Pike,

Affiliation Department of Archaeology, University of Southampton, Highfield, Southampton, United Kingdom
⨯
Jamie Lewis,

Affiliation Bristol Isotope Group, School of Earth Sciences, University of Bristol, Bristol, United Kingdom
⨯
Simon Roffey,

Affiliation Department of Archaeology, University of Winchester, Winchester, United Kingdom
⨯
Philip Marter,

Affiliation Department of Archaeology, University of Winchester, Winchester, United Kingdom
⨯
Oona Y-C Lee,

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Houdini H. T. Wu,

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
David E. Minnikin,

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Gurdyal S. Besra,

Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
⨯
Pushpendra Singh,

Affiliation Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯
Stewart T. Cole,

Affiliation Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯
Graham R. Stewart

Affiliation Department of Microbial and Cellular Science, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, United Kingdom
⨯

Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital

G. Michael Taylor,
Katie Tucker,
Rachel Butler,
Alistair W. G. Pike,
Jamie Lewis,
Simon Roffey,
Philip Marter,
Oona Y-C Lee,
Houdini H. T. Wu,
David E. Minnikin

Published: April 30, 2013
https://doi.org/10.1371/journal.pone.0062406

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Leprosy
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Osteology
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Polymerase chain reaction
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Mycobacterium leprae
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Single nucleotide polymorphisms
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