A Highly Productive, Whole-Cell DERA Chemoenzymatic Process for Production of Key Lactonized Side-Chain Intermediates in Statin Synthesis

• Matej Ošlaj,

  Affiliation Genetics, Anti-Infectives, Lek Pharmaceuticals d.d., Mengeš, Slovenia

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• Jérôme Cluzeau,

  Affiliation API Development, Sandoz Development Center Slovenia, Lek Pharmaceuticals d.d., Mengeš, Slovenia

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• Damir Orkić,

  Affiliation API Development, Sandoz Development Center Slovenia, Lek Pharmaceuticals d.d., Mengeš, Slovenia

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• Gregor Kopitar,

  Affiliation Genetics, Anti-Infectives, Lek Pharmaceuticals d.d., Mengeš, Slovenia

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• Peter Mrak ,

  * E-mail: peter.mrak@sandoz.com (PM); zdenko.casar@sandoz.com (ZC)

  Affiliation Genetics, Anti-Infectives, Lek Pharmaceuticals d.d., Mengeš, Slovenia

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• Zdenko Časar

  * E-mail: peter.mrak@sandoz.com (PM); zdenko.casar@sandoz.com (ZC)

  Affiliations API Development, Sandoz Development Center Slovenia, Lek Pharmaceuticals d.d., Mengeš, Slovenia, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

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