Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?

Jing Lin; Xiling Shou; Xiaobo Mao; Jiangchuan Dong; Nilesh Mohabeer; Kishan kumar Kushwaha; Lei Wang; Yousu Su; Hongcheng Fang; Dazhu Li

doi:10.1371/journal.pone.0062148

Loading metrics

Open Access

Peer-reviewed

Research Article

Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?

Jing Lin ,

Contributed equally to this work with: Jing Lin, Xiling Shou, Xiaobo Mao

Affiliation Department of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, China
⨯
Xiling Shou ,

Contributed equally to this work with: Jing Lin, Xiling Shou, Xiaobo Mao

Affiliation Department of Cardiovascular Medicine, Shaanxi Provincial People's Hospital, Xi'an, China
⨯
Xiaobo Mao ,

Contributed equally to this work with: Jing Lin, Xiling Shou, Xiaobo Mao

Affiliation Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Jiangchuan Dong,

Affiliation Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Nilesh Mohabeer,

Affiliation Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Kishan kumar Kushwaha,

Affiliation Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Lei Wang,

Affiliation Department of Cardiology, Shenzhen Sixth People's Hospital (Nanshan Hospital), Huazhong University of Science and Technology, Union Shenzhen Hospital, Shenzhen, China
⨯
Yousu Su,

Affiliation Department of Cardiology, Shenzhen Sixth People's Hospital (Nanshan Hospital), Huazhong University of Science and Technology, Union Shenzhen Hospital, Shenzhen, China
⨯
Hongcheng Fang,

Affiliation Department of Cardiology, Shenzhen Sixth People's Hospital (Nanshan Hospital), Huazhong University of Science and Technology, Union Shenzhen Hospital, Shenzhen, China
⨯
Dazhu Li

* E-mail: lidazhuhp@sohu.com

Affiliation Department of Cardiology, Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯

Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?

Jing Lin,
Xiling Shou,
Xiaobo Mao,
Jiangchuan Dong,
Nilesh Mohabeer,
Kishan kumar Kushwaha,
Lei Wang,
Yousu Su,
Hongcheng Fang,
Dazhu Li

Published: April 25, 2013
https://doi.org/10.1371/journal.pone.0062148

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Atherosclerosis
Is the Subject Area "Atherosclerosis" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
DNA fragmentation
Is the Subject Area "DNA fragmentation" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.