Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models

Open Access

Peer-reviewed

Research Article

Barzan I. Khayatt,

Current address: Department of Soil and Water Sciences, Faculty of Agricultural Sciences, University of Sulaimani, Sulaimani, Kurdistan, Iraq

Affiliation Center for Molecular and Biomolecular Informatics, Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
⨯
Lex Overmars,

Affiliations Center for Molecular and Biomolecular Informatics, Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands Bioinformatics Center, Nijmegen, The Netherlands
⨯
Roland J. Siezen,

Affiliations Center for Molecular and Biomolecular Informatics, Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands Bioinformatics Center, Nijmegen, The Netherlands, Kluyver Center for Genomics of Industrial Fermentation, Delft, The Netherlands, TI Food and Nutrition, Wageningen, The Netherlands
⨯
Christof Francke

* E-mail: c.francke@cmbi.ru.nl

Affiliations Center for Molecular and Biomolecular Informatics, Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Netherlands Bioinformatics Center, Nijmegen, The Netherlands, Kluyver Center for Genomics of Industrial Fermentation, Delft, The Netherlands, TI Food and Nutrition, Wageningen, The Netherlands
⨯

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Sequence alignment
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Multiple alignment calculation
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Protein domains
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