A Synthetic Podophyllotoxin Derivative Exerts Anti-Cancer Effects by Inducing Mitotic Arrest and Pro-Apoptotic ER Stress in Lung Cancer Preclinical Models

• Jia-Yang Chen,

  Affiliation Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan, R.O.C

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• Yen-An Tang,

  Affiliation Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan, R.O.C

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• Wen-Shan Li,

  Affiliation Institute of Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C

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• Yu-Ching Chiou,

  Affiliations Institute of Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C, Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan, R.O.C

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• Jiunn-Min Shieh ,

  * E-mail: ycw5798@mail.ncku.edu.tw (YCW); shieh225@ms29.hinet.net (JMS)

  Affiliations Division of Chest Medicine, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan, R.O.C, The Center of General Education, Chia Nan University of Pharmacy & Science, Tainan, Taiwan, R.O.C

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• Yi-Ching Wang

  * E-mail: ycw5798@mail.ncku.edu.tw (YCW); shieh225@ms29.hinet.net (JMS)

  Affiliations Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan, R.O.C, Department of Pharmacology, National Cheng Kung University, Tainan, Taiwan, R.O.C

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