Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice

Jung Eun Kim; Mi Hwa Lee; Deok Hwa Nam; Hye Kyoung Song; Young Sun Kang; Ji Eun Lee; Hyun Wook Kim; Jin Joo Cha; Young Youl Hyun; Sang Youb Han; Kum Hyun Han; Jee Young Han; Dae Ryong Cha

doi:10.1371/journal.pone.0062068

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Open Access

Peer-reviewed

Research Article

Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice

Jung Eun Kim,

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯
Mi Hwa Lee,

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯
Deok Hwa Nam,

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯
Hye Kyoung Song,

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯
Young Sun Kang,

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯
Ji Eun Lee,

Affiliation Department of Internal Medicine, Division of Nephrology, Wonkwang University, Gunpo City, Kyungki-Do, Korea
⨯
Hyun Wook Kim,

Affiliation Department of Internal Medicine, Division of Nephrology, Wonkwang University, Gunpo City, Kyungki-Do, Korea
⨯
Jin Joo Cha,

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯
Young Youl Hyun,

Affiliation Department of Internal Medicine, Division of Nephrology, Sungkyunkwan University, Seoul, Korea
⨯
Sang Youb Han,

Affiliation Department of Internal Medicine, Division of Nephrology, Inje University, Goyang City, Kyungki-Do, Korea
⨯
Kum Hyun Han,

Affiliation Department of Internal Medicine, Division of Nephrology, Inje University, Goyang City, Kyungki-Do, Korea
⨯
Jee Young Han,

Affiliation Department of Pathology, Inha University, Incheon City, Kyungki-Do, Korea
⨯
Dae Ryong Cha

* E-mail: cdragn@unitel.co.kr

Affiliation Department of Internal Medicine, Division of Nephrology, Korea University, Ansan City, Kyungki-Do, Korea
⨯

Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice

Jung Eun Kim,
Mi Hwa Lee,
Deok Hwa Nam,
Hye Kyoung Song,
Young Sun Kang,
Ji Eun Lee,
Hyun Wook Kim,
Jin Joo Cha,
Young Youl Hyun,
Sang Youb Han

Published: April 26, 2013
https://doi.org/10.1371/journal.pone.0062068

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