A Novel Function of Novobiocin: Disrupting the Interaction of HIF 1α and p300/CBP through Direct Binding to the HIF1α C-Terminal Activation Domain

• Donglu Wu ,

  Contributed equally to this work with: Donglu Wu, Rui Zhang

  Affiliations College of Life Science, Jilin University, Changchun, Jilin, China, Graduate School of Jilin University, Changchun, Jilin, China

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• Rui Zhang ,

  Contributed equally to this work with: Donglu Wu, Rui Zhang

  Affiliations College of Life Science, Jilin University, Changchun, Jilin, China, Graduate School of Jilin University, Changchun, Jilin, China

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• Rui Zhao,

  Affiliations College of Life Science, Jilin University, Changchun, Jilin, China, Graduate School of Jilin University, Changchun, Jilin, China

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• Guang Chen,

  Affiliation The First Clinical Hospital, Jilin University, Changchun, Jilin, China

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• Yong Cai ,

  * E-mail: caiyong62@jlu.edu.cn (YC); jjjin@jlu.edu.cn (JJ)

  Affiliations College of Life Science, Jilin University, Changchun, Jilin, China, National Engineering Laboratory for AIDS Vaccine, College of Life Science, Jilin University, Changchun, Jilin, China

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• Jingji Jin

  * E-mail: caiyong62@jlu.edu.cn (YC); jjjin@jlu.edu.cn (JJ)

  Affiliations College of Life Science, Jilin University, Changchun, Jilin, China, National Engineering Laboratory for AIDS Vaccine, College of Life Science, Jilin University, Changchun, Jilin, China

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