Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

Luke Barron; Amber M. Smith; Karim C. El Kasmi; Joseph E. Qualls; Xiaozhu Huang; Allen Cheever; Lee A. Borthwick; Mark S. Wilson; Peter J. Murray; Thomas A. Wynn

doi:10.1371/journal.pone.0061961

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Open Access

Peer-reviewed

Research Article

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

Luke Barron ,

* E-mail: BarronL@niaid.nih.gov

Affiliation Program in Barrier Immunity and Repair, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Amber M. Smith,

Affiliation Departments of Infectious Diseases and Immunology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
⨯
Karim C. El Kasmi,

Current address: Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, University of Colorado at Denver, Aurora, Colorado, United States of America

Affiliation Departments of Infectious Diseases and Immunology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
⨯
Joseph E. Qualls,

Current address: Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

Affiliation Departments of Infectious Diseases and Immunology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
⨯
Xiaozhu Huang,

Affiliation Lung Biology Center, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
⨯
Allen Cheever,

Affiliation Biomedical Research Institute, Rockville, Maryland, United States of America
⨯
Lee A. Borthwick,

Affiliation Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
⨯
Mark S. Wilson,

Affiliation Division of Molecular Immunology, National Institute for Medical Research, MRC, London, United Kingdom
⨯
Peter J. Murray,

Affiliation Departments of Infectious Diseases and Immunology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
⨯
Thomas A. Wynn

Affiliation Program in Barrier Immunity and Repair, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

Luke Barron,
Amber M. Smith,
Karim C. El Kasmi,
Joseph E. Qualls,
Xiaozhu Huang,
Allen Cheever,
Lee A. Borthwick,
Mark S. Wilson,
Peter J. Murray,
Thomas A. Wynn

Published: April 24, 2013
https://doi.org/10.1371/journal.pone.0061961

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