Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model

• Lisa G. van den Hengel ,

  Contributed equally to this work with: Lisa G. van den Hengel, Alwine A. Hellingman

  Affiliation Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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• Alwine A. Hellingman ,

  Contributed equally to this work with: Lisa G. van den Hengel, Alwine A. Hellingman

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands

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• Anne Yael Nossent,

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands

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• Annemarie M. van Oeveren-Rietdijk,

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

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• Margreet R. de Vries,

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands

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• C. Arnold Spek,

  Affiliation Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Anton Jan van Zonneveld,

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

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• Pieter H. Reitsma,

  Affiliation Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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• Jaap F. Hamming,

  Affiliation Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands

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• Hetty C. de Boer ,

  ¶These authors also contributed equally to this work.

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

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• Henri H. Versteeg ,

  * E-mail: h.h.versteeg@lumc.nl

  ¶These authors also contributed equally to this work.

  Affiliation Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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• Paul H. A. Quax

  ¶These authors also contributed equally to this work.

  Affiliations Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands, Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands

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