Critical Role of a Survivin/TGF-β/mTORC1 Axis in IGF-I-Mediated Growth of Prostate Epithelial Cells

Kyung Song; Eswar Shankar; Jiayi Yang; Kara L. Bane; Reema Wahdan-Alaswad; David Danielpour

doi:10.1371/journal.pone.0061896

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Peer-reviewed

Research Article

Critical Role of a Survivin/TGF-β/mTORC1 Axis in IGF-I-Mediated Growth of Prostate Epithelial Cells

Kyung Song,

Current address: College of Pharmacy, Wonkwang University, Iksan, Republic of Korea

Affiliation Case Comprehensive Cancer Center Research Laboratories, The Division of General Medical Sciences-Oncology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Eswar Shankar ,

Contributed equally to this work with: Eswar Shankar, Jiayi Yang

Affiliation Case Comprehensive Cancer Center Research Laboratories, The Division of General Medical Sciences-Oncology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Jiayi Yang ,

Contributed equally to this work with: Eswar Shankar, Jiayi Yang

Current address: Eddingpharm, Westlake Village, California, United States of America

Affiliation Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Kara L. Bane,

Affiliation Case Comprehensive Cancer Center Research Laboratories, The Division of General Medical Sciences-Oncology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Reema Wahdan-Alaswad,

Current address: Department of Pathology, University of Colorado Denver, Denver, Colorado, United States of America

Affiliation Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
David Danielpour

* E-mail: dxd49@case.edu

Affiliations Case Comprehensive Cancer Center Research Laboratories, The Division of General Medical Sciences-Oncology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯

Critical Role of a Survivin/TGF-β/mTORC1 Axis in IGF-I-Mediated Growth of Prostate Epithelial Cells

Kyung Song,
Eswar Shankar,
Jiayi Yang,
Kara L. Bane,
Reema Wahdan-Alaswad,
David Danielpour

Published: May 1, 2013
https://doi.org/10.1371/journal.pone.0061896

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13 Jun 2013
22:57 GMT
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Corrections on statistical analysis Posted by DDanielpour-001 on 13 Jun 2013 at 22:57 GMT

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Cell growth
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Prostate gland
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SMAD signaling
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Kinase inhibitors
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