Permeability Enhancers Dramatically Increase Zanamivir Absolute Bioavailability in Rats: Implications for an Orally Bioavailable Influenza Treatment

Open Access

Peer-reviewed

Research Article

Eric H. Holmes ,

* E-mail: eholmes3@hawaii.edu

Affiliation Department of Cell and Molecular Biology, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Harikrishna Devalapally,

Affiliation Absorption Systems, LP, Exton, Pennsylvania, United States of America
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Libin Li,

Affiliation Absorption Systems, LP, Exton, Pennsylvania, United States of America
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Michael L. Perdue,

Affiliation FluSolutions Consulting, LLC, Hilo, Hawaii, United States of America
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Gary K. Ostrander

Current address: Department of Biomedical Sciences, Florida State University, Tallahassee, Florida, United States of America

Affiliation Department of Cell and Molecular Biology, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Permeability
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Neuraminidase inhibitors
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Drug absorption
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Influenza
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Drug therapy
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