Enhanced De Novo Assembly of High Throughput Pyrosequencing Data Using Whole Genome Mapping

Fatma Onmus-Leone; Jun Hang; Robert J. Clifford; Yu Yang; Matthew C. Riley; Robert A. Kuschner; Paige E. Waterman; Emil P. Lesho

doi:10.1371/journal.pone.0061762

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Open Access

Peer-reviewed

Research Article

Enhanced De Novo Assembly of High Throughput Pyrosequencing Data Using Whole Genome Mapping

Fatma Onmus-Leone ,

Contributed equally to this work with: Fatma Onmus-Leone, Jun Hang

* E-mail: Fatma.Onmus-Leone.ctr@us.army.mil (FOL); Jun.Hang.ctr@us.army.mil (JH)

Affiliation Multidrug-Resistant Organism Surveillance Network and Repository, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Jun Hang ,

Contributed equally to this work with: Fatma Onmus-Leone, Jun Hang

* E-mail: Fatma.Onmus-Leone.ctr@us.army.mil (FOL); Jun.Hang.ctr@us.army.mil (JH)

Affiliation Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Robert J. Clifford,

Affiliation Multidrug-Resistant Organism Surveillance Network and Repository, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Yu Yang,

Affiliation Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Matthew C. Riley,

Affiliation Multidrug-Resistant Organism Surveillance Network and Repository, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Robert A. Kuschner,

Affiliation Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Paige E. Waterman,

Affiliation Multidrug-Resistant Organism Surveillance Network and Repository, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Emil P. Lesho

Affiliation Multidrug-Resistant Organism Surveillance Network and Repository, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯

Enhanced De Novo Assembly of High Throughput Pyrosequencing Data Using Whole Genome Mapping

Fatma Onmus-Leone,
Jun Hang,
Robert J. Clifford,
Yu Yang,
Matthew C. Riley,
Robert A. Kuschner,
Paige E. Waterman,
Emil P. Lesho

Published: April 17, 2013
https://doi.org/10.1371/journal.pone.0061762

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Genomics
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Sequence alignment
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Restriction fragment mapping
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Shotgun sequencing
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