Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection

Open Access

Peer-reviewed

Research Article

Faraz M. Alam,

Affiliation Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, United Kingdom
⨯
Claire E. Turner,

Affiliation Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, United Kingdom
⨯
Ken Smith,

Affiliation Department of Pathology and Infectious Diseases, Royal Veterinary College, Hertfordshire, United Kingdom
⨯
Siouxsie Wiles,

Affiliations Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, United Kingdom, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
⨯
Shiranee Sriskandan

* E-mail: s.sriskandan@imperial.ac.uk

Affiliation Section of Infectious Diseases and Immunity, Department of Medicine, Imperial College London, London, United Kingdom
⨯

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Streptococcus pyogenes
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Mouse models
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Nasopharynx
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Streptococcal infections
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Animal models of infection
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Upper respiratory tract infections
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Inflammation
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Molting
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