Decreased Expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4+ T Cells and Peripheral Blood from Tuberculosis Patients

Katja Kleinsteuber; Kerrin Heesch; Stefanie Schattling; Malte Kohns; Claudia Sander-Jülch; Gerhard Walzl; Anneke Hesseling; Ertan Mayatepek; Bernhard Fleischer; Florian M. Marx; Marc Jacobsen

doi:10.1371/journal.pone.0061609

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Open Access

Peer-reviewed

Research Article

Decreased Expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4⁺ T Cells and Peripheral Blood from Tuberculosis Patients

Katja Kleinsteuber ,

Contributed equally to this work with: Katja Kleinsteuber, Kerrin Heesch

Affiliation Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany
⨯
Kerrin Heesch ,

Contributed equally to this work with: Katja Kleinsteuber, Kerrin Heesch

Affiliation Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany
⨯
Stefanie Schattling,

Affiliation Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany
⨯
Malte Kohns,

Affiliation Department of General Pediatrics, Neonatology, Pediatric Cardiology, University Children’s Hospital, Duesseldorf, Germany
⨯
Claudia Sander-Jülch,

Affiliation Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany
⨯
Gerhard Walzl,

Affiliation Division of Molecular Biology and Human Genetics, MRC Centre for Molecular and Cellular Biology, DST and NRF Centre of Excellence for Biomedical TB Research, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
⨯
Anneke Hesseling,

Affiliation Department of Paediatrics and Child Health, Desmond Tutu Tb Centre, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
⨯
Ertan Mayatepek,

Affiliation Department of General Pediatrics, Neonatology, Pediatric Cardiology, University Children’s Hospital, Duesseldorf, Germany
⨯
Bernhard Fleischer,

Affiliation Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany
⨯
Florian M. Marx,

Affiliation Department for Pediatric Pneumology and Immunology, Charité - Universitätsmedizin, Berlin, Germany
⨯
Marc Jacobsen

* E-mail: marc.jacobsen@med.uni-duesseldorf.de

Affiliations Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, Department of General Pediatrics, Neonatology, Pediatric Cardiology, University Children’s Hospital, Duesseldorf, Germany
⨯

Decreased Expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4⁺ T Cells and Peripheral Blood from Tuberculosis Patients

Katja Kleinsteuber,
Kerrin Heesch,
Stefanie Schattling,
Malte Kohns,
Claudia Sander-Jülch,
Gerhard Walzl,
Anneke Hesseling,
Ertan Mayatepek,
Bernhard Fleischer,
Florian M. Marx

Published: April 16, 2013
https://doi.org/10.1371/journal.pone.0061609

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MicroRNAs
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T cells
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Tuberculosis
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Mycobacterium tuberculosis
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Cloning
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Blood
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Cell-mediated immunity
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Protein expression
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