Combined MRI and 31P-MRS Investigations of the ACTA1(H40Y) Mouse Model of Nemaline Myopathy Show Impaired Muscle Function and Altered Energy Metabolism

Charlotte Gineste; Yann Le Fur; Christophe Vilmen; Arnaud Le Troter; Emilie Pecchi; Patrick J. Cozzone; Edna C. Hardeman; David Bendahan; Julien Gondin

doi:10.1371/journal.pone.0061517

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Peer-reviewed

Research Article

Combined MRI and ³¹P-MRS Investigations of the ACTA1(H40Y) Mouse Model of Nemaline Myopathy Show Impaired Muscle Function and Altered Energy Metabolism

Charlotte Gineste,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
⨯
Yann Le Fur,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
⨯
Christophe Vilmen,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
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Arnaud Le Troter,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
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Emilie Pecchi,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
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Patrick J. Cozzone,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
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Edna C. Hardeman,

Affiliation School of Medical Sciences, University of New South Wales, Sydney, Australia
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David Bendahan,

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
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Julien Gondin

* E-mail: julien.gondin@univ-amu.fr

Affiliation Aix-Marseille Université, Centre National de la Recherche Scientifique (CNRS), Centre de Résonance Magnétique Biologique et Médicale (CRMBM) Unité Mixte de Recherche (UMR), Marseille, France
⨯

Combined MRI and ³¹P-MRS Investigations of the ACTA1(H40Y) Mouse Model of Nemaline Myopathy Show Impaired Muscle Function and Altered Energy Metabolism

Charlotte Gineste,
Yann Le Fur,
Christophe Vilmen,
Arnaud Le Troter,
Emilie Pecchi,
Patrick J. Cozzone,
Edna C. Hardeman,
David Bendahan,
Julien Gondin

Published: April 16, 2013
https://doi.org/10.1371/journal.pone.0061517

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