Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells

Ana Juknat; Maciej Pietr; Ewa Kozela; Neta Rimmerman; Rivka Levy; Fuying Gao; Giovanni Coppola; Daniel Geschwind; Zvi Vogel

doi:10.1371/journal.pone.0061462

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Peer-reviewed

Research Article

Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells

Ana Juknat,

Affiliation The Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases, Sackler Faculty of Medicine, Physiology and Pharmacology Department, Tel Aviv University, Tel Aviv, Israel
⨯
Maciej Pietr †,

† Deceased.

Affiliation Neurobiology Department, Weizmann Institute of Science, Rehovot, Israel
⨯
Ewa Kozela,

Affiliations The Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases, Sackler Faculty of Medicine, Physiology and Pharmacology Department, Tel Aviv University, Tel Aviv, Israel, Neurobiology Department, Weizmann Institute of Science, Rehovot, Israel
⨯
Neta Rimmerman,

Affiliations The Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases, Sackler Faculty of Medicine, Physiology and Pharmacology Department, Tel Aviv University, Tel Aviv, Israel, Neurobiology Department, Weizmann Institute of Science, Rehovot, Israel
⨯
Rivka Levy,

Affiliation Neurobiology Department, Weizmann Institute of Science, Rehovot, Israel
⨯
Fuying Gao,

Affiliation Program in Neurogenetics, Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Giovanni Coppola,

Affiliation Program in Neurogenetics, Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Daniel Geschwind,

Affiliation Program in Neurogenetics, Department of Neurology, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Zvi Vogel

* E-mail: zvi.vogel@weizmann.ac.il

Affiliation The Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases, Sackler Faculty of Medicine, Physiology and Pharmacology Department, Tel Aviv University, Tel Aviv, Israel
⨯

Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells

Ana Juknat,
Maciej Pietr,
Ewa Kozela,
Neta Rimmerman,
Rivka Levy,
Fuying Gao,
Giovanni Coppola,
Daniel Geschwind,
Zvi Vogel

Published: April 24, 2013
https://doi.org/10.1371/journal.pone.0061462

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